Genetic variation in CXCL12 and risk of cervical carcinoma: a population-based case-control study.

doi:10.1111/j.1744-313X.2009.00877.x

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Article

Genetic variation in CXCL12 and risk of cervical carcinoma: a population-based case-control study.

International journal of immunogenetics - 1 Dec 2009

Maley S N, Schwartz S M, Johnson L G, Malkki M, Du Q, Daling J R, Li S S, Zhao L P, Petersdorf E W, Madeleine M M

Abstract excerpt

CXCL12 provides a chemotactic signal-directing leucocyte migration and regulates metastatic behaviour of tumour cells. We conducted a population-based case-control study to test the hypothesis that common genetic variation in CXCL12 individual single nucleotide polymorphism (SNP) alleles and haplotypes] is associated with the risk of cervical carcinoma. Cases (n = 917) were residents of western Washington State...

Topics

3' Untranslated Regions
Adolescent
Adult
Aged
Alleles
Carcinoma
Case-Control Studies
Chemokine CXCL12
Female
Gene Expression Regulation, Neoplastic
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haplotypes

Humans

Middle Aged

Neoplasm Invasiveness

Polymorphism, Single Nucleotide

Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 19788587
DOI: 10.1111/j.1744-313X.2009.00877.x
PMCID: PMC2784202

Genes

CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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