Article
Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan.
Omics : a journal of integrative biology - 1 Apr 2009
Lin Gau-Tyan, Tseng Hung-Fu, Yang Cheng-Hong, Hou Ming-Feng, Chuang Li-Yeh, Tai Hsiao-Ting, Tai Ming-Hong, Cheng Yu-Huei, Wen Cheng-Hao, Liu Chih-Shan, Huang Chih-Jen, Wang Chun-Lin, Chang Hsueh-Wei
Abstract excerpt
Many single nucleotide polymorphisms (SNPs) have been found to be associated with breast cancer, but their SNP interactions are seldom addressed. In this study, we focused on the joint effect for SNP combinations of seven CXCL12-related genes involved in major cancer-related pathways. SNP genotyping was determined by PCR-restriction fragment length polymorphism (RFLP) in this study (case = 220, control = 334)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
