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Gene Variations of Chemokine and Chemokine Receptor CXCL12/CXCR4 in Lung Cancer.

Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer - 1 Jan 2023

Ozbayer Cansu, Yagci Emine, Ak Guntulu, Metintas Selma, Metintas Muzaffer, Kurt Hulyam

Abstract excerpt

Lung cancer is the most common type of cancer in the world and about 1 million people die from lung cancer every year in the world. Inflammation is an important factor in the onset, progression and metastasis of lung cancer. The most important regulators of inflammation are chemokines and chemokine receptors. Chemokines induce the proliferation of cancer cells and prevent their apoptosis. Chemokines may...

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PMID: 36749089
DOI: 10.1615/JEnvironPatholToxicolOncol.2022044374

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