Article
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.
Nature genetics - 1 Jul 2010
Quan Cheng, Ren Yun-Qing, Xiang Lei-Hong, Sun Liang-Dan, Xu Ai-E, Gao Xing-Hua, Chen Hong-Duo, Pu Xiong-Ming, Wu Ri-Na, Liang Chao-Zhao, Li Jia-Bin, Gao Tian-Wen, Zhang Jian-Zhong, Wang Xiu-Li, Wang Jun, Yang Rong-Ya, Liang Ling, Yu Jian-Bin, Zuo Xian-Bo, Zhang Sheng-Quan, Zhang Shu-Mei, Chen Gang, Zheng Xiao-Dong, Li Pan, Zhu Jun, Li Yong-Wei, Wei Xiao-Dong, Hong Wei-Song, Ye Ying, Zhang Yong, Wu Wei-Su, Cheng Hui, Dong Pu-Ling, Hu Da-Yan, Li Yang, Li Min, Zhang Xin, Tang Hua-Yang, Tang Xian-Fa, Xu Sheng-Xin, He Su-Min, Lv Yong-Mei, Shen Min, Jiang Hong-Quan, Wang Ying, Li Kai, Kang Xiao-Jing, Liu Yu-Qin, Sun Li, Liu Zhi-Fang, Xie Shao-Qiong, Zhu Cheng-Yao, Xu Qiang, Gao Jin-Ping, Hu Wen-Long, Ni Cheng, Pan Ting-Meng, Li Yun, Yao Sha, He Cai-Feng, Liu Yang-Sheng, Yu Ze-Ying, Yin Xian-Yong, Zhang Feng-Yu, Yang Sen, Zhou Youwen, Zhang Xue-Jun
Abstract excerpt
We conducted a genome-wide association study of generalized vitiligo in the Chinese Han population by genotyping 1,117 cases and 1,429 controls. The 34 most promising SNPs were carried forward for replication in samples from individuals of the Chinese Han (5,910 cases and 9,916 controls) and Chinese Uygur (713 cases and 824 controls) populations. We identified two independent association signals within the major...
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