Article
A single nucleotide polymorphism rs9468925 of MHC region is associated with clinical features of generalized vitiligo in Chinese Han population.
Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Sept 2012
Liu Jianlan, Tang HuaYang, Zuo XianBo, Liang Bo, Wang PeiGuang, Sun LiangDan, Yang Sen, Zhang XueJun
Abstract excerpt
BACKGROUND: Vitiligo has been found to be associated with different HLA antigens in different ethnic groups. In our previous genome-wide association study (GWAS), we identified independent association signal of rs9468925 (P = 2.21 × 10(-33), OR = 0.74) within HLA-C-HLA-B region. OBJECTIVES: To explore the association between rs9468925 polymorphism within MHC and the clinical features of generalized vitiligo....
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