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Article

Improvements to bead-based oligonucleotide ligation SNP genotyping assays.

BioTechniques - 1 Nov 2008

Bruse Shannon, Moreau Michael, Azaro Marco, Zimmerman Ray, Brzustowicz Linda

Abstract excerpt

We describe a bead-based, multiplexed, oligonucleotide ligation assay (OLA) performed on the Luminex flow cytometer. Differences between this method and those previously reported include the use of far fewer beads and the use of a universal oligonucleotide for signal detection. These innovations serve to significantly reduce the cost of the assay, while maintaining robustness and accuracy. Comparisons are made...

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Identifiers

PMID: 19007340
DOI: 10.2144/000112960
PMCID: PMC3987951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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