Article

BLADE-R: streamlined RNA extraction for molecular diagnostics and high-throughput applications

2025-03-29

Abstract excerpt

Efficient nucleic acid extraction and purification are crucial for cellular and molecular biology research, yet they pose challenges for large-scale clinical RNA sequencing and PCR assays. Here, we present BLADE-R, a magnetic bead-based protocol that simplifies the process by combining cellular lysis and nucleic acid binding into a single step, followed by a unique on-bead rinse for nuclease-free separation of gen...

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Literature Corpus work: a3d49e71-206d-5f81-b6cd-d2d10504df4c
DOI: 10.1101/2025.03.27.645479

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