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Article

Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish.

Biology open - 15 Feb 2022

Diamond Kelly M, Rolfe Sara M, Kwon Ronald Y, Maga A Murat

Abstract excerpt

Due to the complexity of fish skulls, previous attempts to classify craniofacial phenotypes have relied on qualitative features or sparce 2D landmarks. In this work we aim to identify previously unknown 3D craniofacial phenotypes with a semiautomated pipeline in adult zebrafish mutants. We first estimate a synthetic 'normative' zebrafish template using MicroCT scans from a sample pool of wild-type animals using...

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Identifiers

PMID: 35072203
DOI: 10.1242/bio.058948
PMCID: PMC8864294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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