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Article

Tissue-specific multi-omics analysis of atrial fibrillation.

Nature communications - 21 Jan 2022

Assum Ines, Krause Julia, Scheinhardt Markus O, Müller Christian, Hammer Elke, Börschel Christin S, Völker Uwe, Conradi Lenard, Geelhoed Bastiaan, Zeller Tanja, Schnabel Renate B, Heinig Matthias

Abstract excerpt

Genome-wide association studies (GWAS) for atrial fibrillation (AF) have uncovered numerous disease-associated variants. Their underlying molecular mechanisms, especially consequences for mRNA and protein expression remain largely elusive. Thus, refined multi-omics approaches are needed for deciphering the underlying molecular networks. Here, we integrate genomics, transcriptomics, and proteomics of human atrial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35064145
DOI: 10.1038/s41467-022-27953-1
PMCID: PMC8782899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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