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Article

Integrative Omics Approach to Identifying Genes Associated With Atrial Fibrillation.

Circulation research - 31 Jan 2020

Wang Biqi, Lunetta Kathryn L, Dupuis Josée, Lubitz Steven A, Trinquart Ludovic, Yao Lixia, Ellinor Patrick T, Benjamin Emelia J, Lin Honghuang

Abstract excerpt

Rationale: GWAS (Genome-Wide Association Studies) have identified hundreds of genetic loci associated with atrial fibrillation (AF). However, these loci explain only a small proportion of AF heritability. Objective: To develop an approach to identify additional AF-related genes by integrating multiple omics data. Methods and Results: Three types of omics data were integrated: (1) summary statistics from the AFGen...

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Identifiers

PMID: 31801406
DOI: 10.1161/CIRCRESAHA.119.315179
PMCID: PMC7004281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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