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Discriminatory Weight of SNPs in Spike SARS-CoV-2 Variants: A Technically Rapid, Unambiguous, and Bioinformatically Validated Laboratory Approach.

Viruses - 11 Jan 2022

Musso Nicolò, Bonacci Paolo Giuseppe, Bongiorno Dafne, Stracquadanio Stefano, Bivona Dalida Angela, Palermo Concetta Ilenia, Scalia Guido, Fichera Marco, Stefani Stefania

Abstract excerpt

BACKGROUND: The SARS-CoV-2 virus has assumed considerable importance during the COVID-19 pandemic. Its mutation rate is high, involving the spike (S) gene and thus there has been a rapid spread of new variants. Herein, we describe a rapid, easy, adaptable, and affordable workflow to uniquely identify all currently known variants through as few analyses. Our method only requires two conventional PCRs of the S gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35062327
DOI: 10.3390/v14010123
PMCID: PMC8781109

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