Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SpikeID: Rapid and unbiased identification of SARS-CoV-2 variants by spike sequencing.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Oct 2025

Farrugia Keith, Khalil Zain, van de Guchte Adriana, Alburquerque Bremy, Floda Daniel, Srivastava Komal, Patiño Luz H, Ramirez Juan David, Paniz-Mondolfi Alberto E, Sordillo Emilia Mia, Simon Viviana, Gonzalez-Reiche Ana S, van Bakel Harm

Abstract excerpt

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) are characterized by distinct mutations in the S1 domain of the viral spike protein. This domain encompasses the N-terminal domain, the receptor-binding domain, and part of the cleavage site region. While mutations in other genomic regions of SARS-CoV-2 can impact VOC potential, the S1 domain holds particular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Mutation

Share to SARS-CoV-2

Share to Spike Glycoprotein, Coronavirus

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 40774230
DOI: 10.1016/j.jcv.2025.105845
PMCID: PMC13262703

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SpikeID: Rapid and unbiased identification of SARS-CoV-2 variants by spike sequencing.PMID 40774230Read ↗

Efficient SARS-CoV-2 variant detection and monitoring with Spike Screen next-generation sequencing.Semantic proximity Read ↗

SpikeSeq: A rapid, cost efficient and simple method to identify SARS-CoV-2 variants of concern by Sanger sequencing part of the spike protein gene.Semantic proximity Read ↗

Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York.Semantic proximity Read ↗

SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021.Semantic proximity Read ↗

Identification of SARS-CoV-2 Variants of Concern Using Amplicon Next-Generation Sequencing.Semantic proximity Read ↗

HiSpike: A high-throughput cost effective sequencing method for the SARS-CoV-2 spike geneSemantic proximity Read ↗

Large-scale population analysis of SARS-CoV-2 whole genome sequences reveals host-mediated viral evolution with emergence of mutations in the viral Spike protein associated with elevated mortality ratesSemantic proximity Read ↗

Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolatesSemantic proximity Read ↗

Multiplex SARS-CoV-2 Genotyping PCR for Population-Level Variant Screening and Epidemiologic SurveillanceSemantic proximity Read ↗

Comparative genotyping of SARS-CoV-2 among Egyptian patients: near-full length genomic sequences versus selected spike and nucleocapsid regions.Semantic proximity Read ↗

Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates.Semantic proximity Read ↗

HiSpike: A high-throughput cost effective sequencing method for the SARS-CoV-2 spike geneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.