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Article

Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion.

Viruses - 5 Jan 2022

Pandey Kannu Priya, Zhou Yan

Abstract excerpt

The NLRP3 inflammasome consists of NLRP3, ASC, and pro-caspase-1 and is an important arm of the innate immune response against influenza A virus (IAV) infection. Upon infection, the inflammasome is activated, resulting in the production of IL-1β and IL-18, which recruits other immune cells to the site of infection. It has been suggested that in the presence of stress molecules such as nigericin, the trans-Golgi...

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Identifiers

PMID: 35062292
DOI: 10.3390/v14010088
PMCID: PMC8778788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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