Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Encephalomyocarditis Virus Viroporin 2B Activates NLRP3 Inflammasome

9 Aug 2012

Abstract excerpt

Nod-like receptors (NLRs) comprise a large family of intracellular pattern- recognition receptors. Members of the NLR family assemble into large multiprotein complexes, termed the inflammasomes. The NLR family, pyrin domain-containing 3 (NLRP3) is triggered by a diverse set of molecules and signals, and forms the NLRP3 inflammasome. Recent studies have indicated that both DNA and RNA viruses stimulate the NLRP3...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammasome and immune disorders
Share to interferon and immune responses
Share to Kawasaki Disease and Coronary Complications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22916014
DOI: 10.1371/journal.ppat.1002857

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Encephalomyocarditis Virus Viroporin 2B Activates NLRP3 InflammasomePMID 22916014Read ↗

The NLRP3 Inflammasome Detects Encephalomyocarditis Virus and Vesicular Stomatitis Virus InfectionSemantic proximity Read ↗

RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium effluxSemantic proximity Read ↗

PRRSV-2 nsp2 Ignites NLRP3 inflammasome through IKKβ-dependent dispersed trans-Golgi network translocationSemantic proximity Read ↗

The multifaceted roles of NLRP3-modulating proteins in virus infectionSemantic proximity Read ↗

NLRP3 Inflammasome—A Key Player in Antiviral ResponsesSemantic proximity Read ↗

The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infectionSemantic proximity Read ↗

Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and PathogenesisSemantic proximity Read ↗

Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion.Semantic proximity Read ↗

NOD2 (Nucleotide-Binding Oligomerization Domain 2) Is a Major Pathogenic Mediator of Coxsackievirus B3-Induced Myocarditis.Semantic proximity Read ↗

Sendai Virus V Protein Inhibits the Secretion of Interleukin-1β by Preventing NLRP3 Inflammasome AssemblySemantic proximity Read ↗

SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell deathSemantic proximity Read ↗

Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particlesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.