Article
Intra-Host SARS-CoV-2 Evolution in the Gut of Mucosally-Infected Chlorocebus aethiops (African Green Monkeys).
Viruses - 1 Jan 2022
Rowe Lori A, Beddingfield Brandon J, Goff Kelly, Killeen Stephanie Z, Chirichella Nicole R, Melton Alexandra, Roy Chad J, Maness Nicholas J
Abstract excerpt
In recent months, several SARS-CoV-2 variants have emerged that enhance transmissibility and escape host humoral immunity. Hence, the tracking of viral evolutionary trajectories is clearly of great importance. Little is known about SARS-CoV-2 evolution in nonhuman primate models used to test vaccines and therapies and to model human disease. Viral RNA was sequenced from rectal swabs from Chlorocebus aethiops...
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