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Article

UK B.1.1.7 (Alpha) variant exhibits increased respiratory replication and shedding in nonhuman primates.

Emerging microbes & infections - 1 Dec 2021

Rosenke Kyle, Feldmann Friederike, Okumura Atsushi, Hansen Frederick, Tang-Huau Tsing-Lee, Meade-White Kimberly, Kaza Benjamin, Callison Julie, Lewis Matthew C, Smith Brian J, Hanley Patrick W, Lovaglio Jamie, Jarvis Michael A, Shaia Carl, Feldmann Heinz

Abstract excerpt

The continuing emergence of SARS-CoV-2 variants calls for regular assessment to identify differences in viral replication, shedding and associated disease. In this study, we compared African green monkeys infected intranasally with either the UK B.1.1.7 (Alpha) variant or its contemporary D614G progenitor. Both variants caused mild respiratory disease with no significant differences in clinical presentation....

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Identifiers

PMID: 34724885
DOI: 10.1080/22221751.2021.1997074
PMCID: PMC8635622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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