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Article

Prevalence of targeted therapy-related genetic variations in NSCLC and their relationship with clinicopathological characteristics.

PloS one - 1 Jan 2022

Li Fanghua, Ye Peng, Cai Peiling, Dong Dandan, Zhang Yihao, Yang Yue, Sun Xingwang

Abstract excerpt

BACKGROUND: Non-small cell lung cancer (NSCLC) is the most common cancer type in China. Targeted therapies have been used to treat NSCLC for two decades, which is only suitable for a subgroup of patients with specific genetic variations. The aim of this study was to investigate the prevalence of genetic variations leading to sensitivity or resistance to targeted therapies in NSCLC, and their relationship with...

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Identifiers

PMID: 35061839
DOI: 10.1371/journal.pone.0262822
PMCID: PMC8782298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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