Article
Molecular Epidemiology of the Main Druggable Genetic Alterations in Non-Small Cell Lung Cancer.
International journal of molecular sciences - 9 Jan 2021
Fois Sara S, Paliogiannis Panagiotis, Zinellu Angelo, Fois Alessandro G, Cossu Antonio, Palmieri Giuseppe
Abstract excerpt
Lung cancer is the leading cause of death for malignancy worldwide. Its molecular profiling has enriched our understanding of cancer initiation and progression and has become fundamental to provide guidance on treatment with targeted therapies. Testing the presence of driver mutations in specific genes in lung tumors has thus radically changed the clinical management and outcomes of the disease. Numerous studies...
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