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Testing Mitochondrial-Targeted Drugs in iPSC-RPE from Patients with Age-Related Macular Degeneration

4 Jan 2022

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. No universally effective treatments exist for atrophic or "dry" AMD, which results from loss of the retinal pigment epithelium (RPE) and photoreceptors and accounts for ≈80% of all AMD patients. Prior studies provide evidence for the involvement of mitochondrial dysfunction in AMD pathology. This study used induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35056119
DOI: 10.3390/ph15010062

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