Article
The role of mitochondrial DNA mutations in coronary heart disease.
European review for medical and pharmacological sciences - 1 Aug 2020
Ding Y, Gao B-B, Huang J-Y
Abstract excerpt
Coronary heart disease (CHD) is a leading cause of death worldwide. It is a multifactorial disorder resulting from harmful interactions between genetic and environmental factors. Due to the central role of mitochondria in cellular energy homeostasis, there is growing evidence supporting the role of damage to mitochondrial components such as mitochondrial DNA (mtDNA) in the pathogenesis and progression of CHD....
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