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Elevated Expression of JMJD5 Protein Due to Decreased miR-3656 Levels Contributes to Cancer Stem Cell-Like Phenotypes under Overexpression of Cancer Upregulated Gene 2.

Biomolecules - 12 Jan 2022

Yawut Natpaphan, Cho Il-Rae, Budluang Phatcharaporn, Kaowinn Sirichat, Kaewpiboon Chutima, Jeon Byeoleun, Kim Sang-Woo, Kang Ho Young, Kang Min-Kyung, Koh Sang Seok, Chung Young-Hwa

Abstract excerpt

Overexpression of cancer upregulated gene (CUG) 2 induces cancer stem cell-like phenotypes, such as enhanced epithelial-mesenchymal transition, sphere formation, and doxorubicin resistance. However, the precise mechanism of CUG2-induced oncogenesis remains unknown. We evaluated the effects of overexpression of CUG2 on microRNA levels using a microRNA microarray. Levels of miR-3656 were decreased when CUG2 was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 35053270
DOI: 10.3390/biom12010122
PMCID: PMC8774111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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