Article

The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer

2023-07-31

Abstract excerpt

<title>Abstract</title> <p>Background Chemoresistance remains the primary cause of mortality in colorectal cancer (CRC). However, our understanding of the molecular basis underlying CRC chemoresistance is still limited. Elongation factor Tu GTP binding domain containing 2 (EFTUD2) has been implicated as a potential oncogenic factor in various cancer types, yet its specific role in regulating the sensitivity of C...

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Literature Corpus work: edf1808d-e8ed-58e1-b5db-87c483939495
DOI: 10.21203/rs.3.rs-3188701/v1

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