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Article

The Skin and Nose Microbiome and Its Association with Filaggrin Gene Mutations in Pediatric Atopic Dermatitis.

Dermatology (Basel, Switzerland) - 1 Jan 2022

van Mierlo Minke M F, Pardo Luba M, Fieten Karin B, van den Broek Tim J, Schuren Frank H J, van Geel Michel, Pasmans Suzanne G M A

Abstract excerpt

BACKGROUND: Interactions between the skin barrier, immune system, and microbiome underlie the development of atopic dermatitis (AD). OBJECTIVE: To investigate the skin and nasal microbiome in relation to filaggrin gene (FLG) mutations. METHODS: A cross-sectional study including 77 children with difficult-to-treat AD. The entire encoding region of FLG was screened for mutations using single molecule molecular...

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Identifiers

PMID: 35042220
DOI: 10.1159/000520978
PMCID: PMC9501786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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