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Article

Association of Disease Severity With Skin Microbiome and Filaggrin Gene Mutations in Adult Atopic Dermatitis.

JAMA dermatology - 1 Mar 2018

Clausen Maja-Lisa, Agner Tove, Lilje Berit, Edslev Sofie M, Johannesen Thor Bech, Andersen Paal Skytt

Abstract excerpt

Importance: Skin microbiome correlates with disease severity for lesional and nonlesional skin, indicating a global influence of atopic dermatitis (AD). A relation between skin microbiome and filaggrin gene (FLG) mutations proposes a possible association between skin microbiome and host genetics. Objectives: To assess skin and nasal microbiome diversity and composition in patients with AD and compare with healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29344612
DOI: 10.1001/jamadermatol.2017.5440
PMCID: PMC5885821

Genes

FLG

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