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Article

Genetic/Environmental Contributions and Immune Dysregulation in Children with Atopic Dermatitis

1 Nov 2022

Abstract excerpt

Abstract: Atopic dermatitis (AD) is one of the most common skin conditions in humans. AD affects up to 20% of children worldwide and results in morbidity for both patients and their caregivers. The basis of AD is an interplay between genetics and the environment characterized by immune dysregulation. A myriad of mutations that compromise the skin barrier and/or immune function have been linked to AD. Of these,...

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PMID: 36447957
DOI: 10.2147/jaa.s293900

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