Article
Atopic dermatitis microbiomes stratify into ecologic dermotypes enabling microbial virulence and disease severity.
The Journal of allergy and clinical immunology - 1 Apr 2021
Tay Angeline S L, Li Chenhao, Nandi Tannistha, Chng Kern Rei, Andiappan Anand Kumar, Mettu Vijaya Saradhi, de Cevins Camille, Ravikrishnan Aarthi, Dutertre Charles-Antoine, Wong X F Colin C, Ng Amanda Hui Qi, Matta Sri Anusha, Ginhoux Florent, Rötzschke Olaf, Chew Fook Tim, Tang Mark B Y, Yew Yik Weng, Nagarajan Niranjan, Common John E A
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a common skin disease affecting up to 20% of the global population, with significant clinical heterogeneity and limited information about molecular subtypes and actionable biomarkers. Although alterations in the skin microbiome have been described in subjects with AD during progression to flare state, the prognostic value of baseline microbiome configurations has not been...
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