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Article

Serum-free cultures of C2C12 cells show different muscle phenotypes which can be estimated by metabolic profiling.

Scientific reports - 17 Jan 2022

Jang Mi, Scheffold Jana, Røst Lisa Marie, Cheon Hyejeong, Bruheim Per

Abstract excerpt

In vitro skeletal muscle cell production is emerging in the field of artificial lab-grown meat as alternative future food. Currently, there is an urgent paradigm shift towards a serum replacement culture system. Surprisingly, little is known about the impact of serum-free culture on skeletal muscle cells to date. Therefore, we performed metabolic profiling of the C2C12 myoblasts and myotubes in serum-free mediums...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35039582
DOI: 10.1038/s41598-022-04804-z
PMCID: PMC8764040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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