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Article

Predisposition of SOD1, GPX1, CAT genetic variants and their haplotypes in cataractogenesis of type 2 diabetes mellitus in Pakistan.

Acta diabetologica - 1 May 2022

Kafeel Sanober, Hashim Zehra, Fawwad Asher, Nawab Syeda Nuzhat

Abstract excerpt

AIMS: Cataract formation is accelerated by hyperglycemia due to the excessive production of oxidative stress. This study aimed to examine the underlaying role of glutathione peroxidase 1 (GPX1) rs1800668, catalase (CAT) rs1001179 and superoxide dismutase 1 (SOD1) 50 bp Indel promotor region variants in the pathogenesis of cataract in patients with diabetes. METHODS: A population-based case-control study of n=680...

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PMID: 35037135
DOI: 10.1007/s00592-021-01832-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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