Article
A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract.
Investigative ophthalmology & visual science - 1 Apr 2016
Chang Cheng, Zhang Kaida, Veluchamy Abirami, Hébert Harry L, Looker Helen C, Colhoun Helen M, Palmer Colin N A, Meng Weihua
Abstract excerpt
PURPOSE: Diabetic cataract is one of the major eye complications of diabetes. It was reported that cataract occurs two to five times more frequently in patients with diabetes compared with those with no diabetes. The purpose of this study was to identify genetic contributors of diabetic cataract based on a genome-wide association approach using a well-defined Scottish diabetic cohort. METHODS: We adapted linked...
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