Article
Consistency evaluation of lung adenocarcinoma tissue and circulating tumor cells related gene mutation detection based on multi-site immunomagnetic beads.
Journal of biomaterials applications - 1 Apr 2022
Xue Keying, Luo Bingqing, Li Xiaoqing, Deng Weixian, Zeng Chunyan, Zuo Cuiyun
Abstract excerpt
This study was designed to investigate the feasibility of genetic testing using circulating tumor cells (CTCs) instead of tumor tissues in lung adenocarcinoma to break through its limitation. Separation system for epithelial cell adhesion molecule (EpCAM), epidermal growth factor receptor (EGFR), and Vimentin expressing CTCs was constructed and used to capture CTCs in the blood samples of 57 patients with lung...
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