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Article

Sorting and gene mutation verification of circulating tumor cells of lung cancer with epidermal growth factor receptor peptide lipid magnetic spheres.

Thoracic cancer - 1 Oct 2020

Wang Sheng-Guang, Zhang Bin, Li Chen-Guang, Zhu Jian-Quan, Sun Bing-Sheng, Wang Chang-Li

Abstract excerpt

BACKGROUND: This study aimed to identify an efficient, simple, and specific method of detecting mutations in the epidermal growth factor receptor (EGFR) gene in isolated lung cancer circulating tumor cells (CTCs) and to improve the ability to obtain tumor tissue clinically. METHODS: EGFR peptide lipid magnetic spheres (EG-P-LMB) were prepared by reverse evaporation, and characterization and cell capture...

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Identifiers

PMID: 32856417
DOI: 10.1111/1759-7714.13625
PMCID: PMC7529546

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EGFR

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