Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic impact of circulating tumor cells detected with the microfluidic "universal CTC-chip" for primary lung cancer.

Cancer science - 1 Mar 2022

Kanayama Masatoshi, Kuwata Taiji, Mori Masataka, Nemoto Yukiko, Nishizawa Natsumasa, Oyama Rintaro, Matsumiya Hiroki, Taira Akihiro, Shinohara Shinji, Takenaka Masaru, Yoneda Kazue, Kuroda Koji, Ohnaga Takashi, Tanaka Fumihiro

Abstract excerpt

Detecting rare circulating tumor cells (CTCs) in the bloodstream is extremely challenging. We had previously developed a novel polymeric microfluidic device, "CTC-chip," for capturing CTCs and have shown high capture efficiency in lung cancer cell lines by conjugating Abs against epithelial cell adhesion molecules (EpCAM). This study aimed to optimize the EpCAM-chip and clarify the prognostic impact of CTCs in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Disease-Free Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cell Adhesion Molecule

Share to Lab-On-A-Chip Devices

Share to Lung Neoplasms

Share to Microfluidic Analytical Techniques

Share to Neoplastic Cells, Circulating

Share to Progression-Free Survival

Source

Open in PubMed Open full text

Identifiers

PMID: 34964211
DOI: 10.1111/cas.15255
PMCID: PMC8898730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic impact of circulating tumor cells detected with the microfluidic "universal CTC-chip" for primary lung cancer.PMID 34964211Read ↗

An Integrated Microfluidic Chip and Its Clinical Application for Circulating Tumor Cell Isolation and Single‐Cell AnalysisSemantic proximity Read ↗

Development and clinical validation of a microfluidic-based platform for CTC enrichment and downstream molecular analysisSemantic proximity Read ↗

Highly sensitive detection and mutational analysis of lung cancer circulating tumor cells using integrated combined immunomagnetic beads with a droplet digital PCR chip.Semantic proximity Read ↗

EGFR mutation detection of lung circulating tumor cells using a multifunctional microfluidic chip.Semantic proximity Read ↗

Consistency evaluation of lung adenocarcinoma tissue and circulating tumor cells related gene mutation detection based on multi-site immunomagnetic beads.Semantic proximity Read ↗

Capture of circulating metastatic cancer cell clusters from a lung cancer patient can reveal a unique genomic profile and potential anti-metastatic molecular targets: A proof of concept studySemantic proximity Read ↗

A Microfluidic Chip for Efficient Circulating Tumor Cells Enrichment, Screening, and Single‐Cell RNA SequencingSemantic proximity Read ↗

Molecular profiling of single circulating tumor cells from lung cancer patients.Semantic proximity Read ↗

Monitoring of cancer patients via next‐generation sequencing of patient‐derived circulating tumor cells and tumor DNASemantic proximity Read ↗

Development and clinical validation of a microfluidic-based platform for CTC enrichment and downstream molecular analysisSemantic proximity Read ↗

Vertical Magnetic Separation of Circulating Tumor Cells for Somatic Genomic-Alteration Analysis in Lung Cancer Patients.Semantic proximity Read ↗

High-Density Dielectrophoretic Microwell Array for Detection, Capture, and Single-Cell Analysis of Rare Tumor Cells in Peripheral BloodSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.