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Article

Polymorphism of the HLA system and weak antibody response to BNT162b2 mRNA vaccine.

HLA - 1 Mar 2022

Crocchiolo Roberto, Gallina Anna Maria, Pani Arianna, Campisi Daniela, Cento Valeria, Sacchi Nicoletta, Miotti Valeria, Gagliardi Oscar Matteo, D'Amico Federico, Vismara Chiara, Cornacchini Giorgia, Lando Giuliana, Cuppari Irene, Scaglione Francesco, Rossini Silvano

Abstract excerpt

The polymorphism of the HLA system has been extensively studied in COVID-19 infection, however there are no data about the role of HLA on vaccine response. We report here the HLA-A, -B, -C, and DRB1 allelic frequencies of n = 111 individuals after BNT162b2 mRNA vaccine, selected on the basis of lower antibody levels (<5% percentile) after the second dose among a total of n = 2569 vaccinees, and compare them with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35025131
DOI: 10.1111/tan.14546

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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