Article
Relationship between HLA-II Gene Polymorphisms and Immune Response in COVID-19 Survivors and Volunteers Vaccinated against This Infection.
Bulletin of experimental biology and medicine - 1 Sept 2024
Dubrovina V I, Bryukhova D D, Korytov K M, Pyatidesyatnikova A B, Vishnyakov V A, Balakhonov S V
Abstract excerpt
The polymorphism of HLA class II genes was studied in COVID-19 survivors and vaccinated people. Six allelic variants of DQA1, 10 of DQB1, and 11 of DRB1 were identified. The DQA1*05:01 allele predominated in vaccinated volunteers and the DQA1*02:01, *01:03, and DQB1*06:02-8 alleles predominated in convalescents. In the groups with DQA1*01:01, *05:01 and *06:01 alleles, a high proportion of individuals...
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