Article
Dynamic susceptibility contrast-MRI parameters, ADC values, and the T2-FLAIR mismatch sign are useful to differentiate between H3-mutant and H3-wild-type high-grade midline glioma.
European radiology - 1 Jun 2022
Kurokawa Ryo, Kurokawa Mariko, Baba Akira, Ota Yoshiaki, Kim John, Capizzano Aristides, Srinivasan Ashok, Moritani Toshio
Abstract excerpt
OBJECTIVES: Diffuse midline gliomas, H3K27-altered (DMG-A), are malignant gliomas with an unfavorable prognosis. Knowledge of dynamic susceptibility contrast (DSC) MRI findings and imaging differences with high-grade midline glioma without H3K27 alteration (DMG-W) has been limited. We compared the DSC, ADC, and conventional MRI findings between DMG-A and DMG-W. METHODS: In this single institutional retrospective...
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