Article
Diffusion Characteristics of Pediatric Diffuse Midline Gliomas with Histone H3-K27M Mutation Using Apparent Diffusion Coefficient Histogram Analysis.
AJNR. American journal of neuroradiology - 1 Nov 2019
Aboian M S, Tong E, Solomon D A, Kline C, Gautam A, Vardapetyan A, Tamrazi B, Li Y, Jordan C D, Felton E, Weinberg B, Braunstein S, Mueller S, Cha S
Abstract excerpt
BACKGROUND AND PURPOSE: Diffuse midline gliomas with histone H3 K27M mutation are biologically aggressive tumors with poor prognosis defined as a new diagnostic entity in the 2016 World Health Organization Classification of Tumors of the Central Nervous System. There are no qualitative imaging differences (enhancement, border, or central necrosis) between histone H3 wildtype and H3 K27M-mutant diffuse midline...
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