Article
Diffusion and perfusion imaging biomarkers of H3 K27M mutation status in diffuse midline gliomas.
Neuroradiology - 1 Aug 2022
Kathrani Nihar, Chauhan Richa Singh, Kotwal Abhishek, Kulanthaivelu Karthik, Bhat Maya Dattatraya, Saini Jitender, Prasad Chandrajit, Chakrabarti Dhritiman, Santosh Vani, Uppar Alok Mohan, Srinivas Dwarakanath
Abstract excerpt
PURPOSE: H3K27M-mutant diffuse midline gliomas (M-DMGs) exhibit a clinically aggressive course. We studied diffusion-weighted imaging (DWI) and perfusion (PWI) MRI features of DMG with the hypothesis that DWI-PWI metrics can serve as biomarkers for the prediction of the H3K27M mutation status in DMGs. METHODS: A retrospective review of the institutional database (imaging and histopathology) of patients with DMG...
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