Article
Deep Learning for Noninvasive Assessment of H3 K27M Mutation Status in Diffuse Midline Gliomas Using MR Imaging.
Journal of magnetic resonance imaging : JMRI - 1 Sept 2023
Li Junjie, Zhang Peng, Qu Liying, Sun Ting, Duan Yunyun, Wu Minghao, Weng Jinyuan, Li Zhaohui, Gong Xiaodong, Liu Xing, Wang Yongzhi, Jia Wenqing, Su Xiaorui, Yue Qiang, Li Jianrui, Zhang Zhiqiang, Barkhof Frederik, Huang Raymond Y, Chang Ken, Sair Haris, Ye Chuyang, Zhang Liwei, Zhuo Zhizheng, Liu Yaou
Abstract excerpt
BACKGROUND: Determination of H3 K27M mutation in diffuse midline glioma (DMG) is key for prognostic assessment and stratifying patient subgroups for clinical trials. MRI can noninvasively depict morphological and metabolic characteristics of H3 K27M mutant DMG. PURPOSE: This study aimed to develop a deep learning (DL) approach to noninvasively predict H3 K27M mutation in DMG using T2-weighted images. STUDY TYPE:...
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