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Article

Imaging features associated with H3 K27-altered and H3 G34-mutant gliomas: a narrative systematic review.

Cancer imaging : the official publication of the International Cancer Imaging Society - 17 Nov 2022

Lasocki Arian, Abdalla Gehad, Chow Geoffrey, Thust Stefanie C

Abstract excerpt

BACKGROUND: Advances in molecular diagnostics accomplished the discovery of two malignant glioma entities harboring alterations in the H3 histone: diffuse midline glioma, H3 K27-altered and diffuse hemispheric glioma, H3 G34-mutant. Radiogenomics research, which aims to correlate tumor imaging features with genotypes, has not comprehensively examined histone-altered gliomas (HAG). The aim of this research was to...

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Identifiers

PMID: 36397143
DOI: 10.1186/s40644-022-00500-3
PMCID: PMC9673447

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