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Article

Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/α-ketoglutarate-dependent oxygenase SptF.

Nature communications - 10 Jan 2022

Tao Hui, Mori Takahiro, Chen Heping, Lyu Shuang, Nonoyama Akihito, Lee Shoukou, Abe Ikuro

Abstract excerpt

Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze various oxidative biotransformations. Due to their catalytic flexibility and high efficiency, Fe/αKG oxygenases have attracted keen attention for their application as biocatalysts. Here, we report the biochemical and structural characterizations of the unusually promiscuous and catalytically versatile Fe/αKG oxygenase SptF, involved in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35013177
DOI: 10.1038/s41467-021-27636-3
PMCID: PMC8748661

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