Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monooxygenase-catalyzed regioselective hydroxylation for the synthesis of hydroxyequols

1 Jan 2019

Abstract excerpt

Monooxygenases exhibiting high activity and differing regioselectivity for the dietary isoflavone metabolite equol were discovered among enzymes in the HpaBC family by a genome mining approach. These enzymes enabled the one-step product-selective synthesis of 3'- and 6-hydroxyequols from equol and molecular oxygen.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet, Metabolism, and Disease
Share to Natural Antidiabetic Agents Studies
Share to Phytoestrogen effects and research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35518870
DOI: 10.1039/c9ra03913a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monooxygenase-catalyzed regioselective hydroxylation for the synthesis of hydroxyequolsPMID 35518870Read ↗

Characterization and Identification of a New Daidzein Reductase Involved in (S)-Equol Biosynthesis in Clostridium sp. ZJ6Semantic proximity Read ↗

P212A Mutant of Dihydrodaidzein Reductase Enhances (S)-Equol Production and Enantioselectivity in a Recombinant Escherichia coli Whole-Cell Reaction System.Semantic proximity Read ↗

A Whole-Cell Catalytic System for Equol Production Based on Daidzein Reductase Engineering.Semantic proximity Read ↗

Transcriptional Regulation of the Equol Biosynthesis Gene Cluster in Adlercreutzia equolifaciens DSM19450TSemantic proximity Read ↗

Characterization and identification of a novel daidzein reductase involved in ( <i>S</i> )-equol biosynthesis in Clostridium C1Semantic proximity Read ↗

Taxonomic distribution and evolutionary analysis of the equol biosynthesis gene clusterSemantic proximity Read ↗

Gut Microbiota-Assisted Synthesis, Cellular Interactions and Synergistic Perspectives of Equol as a Potent Anticancer IsoflavoneSemantic proximity Read ↗

High Titer of (S)-Equol Synthesis from Daidzein in Escherichia coliSemantic proximity Read ↗

Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/α-ketoglutarate-dependent oxygenase SptF.Semantic proximity Read ↗

Isoflavonoid metabolism in leguminous plants: an update and perspectivesSemantic proximity Read ↗

The importance of the dihydrodaidzein racemase and dihydrodaidzein reductase activities and the host microorganism to achieve an efficient equol production by engineered lactic acid bacteriaSemantic proximity Read ↗

Cloning and Expression of a Novel NADP(H)-Dependent Daidzein Reductase, an Enzyme Involved in the Metabolism of Daidzein, from Equol-Producing <i>Lactococcus</i> Strain 20-92Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.