Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impacts of genotypic variants on survival following reoperation for recurrent glioblastoma.

Journal of neuro-oncology - 1 Jan 2022

Dono Antonio, Zhu Ping, Holmes Emma, Takayasu Takeshi, Zhu Jay-Jiguang, Blanco Angel I, Hsu Sigmund, Bhattacharjee Meenakshi B, Ballester Leomar Y, Kim Dong H, Esquenazi Yoshua, Tandon Nitin

Abstract excerpt

INTRODUCTION: Recurrent glioblastoma (rGBM) prognosis is dismal. In the absence of effective adjuvant treatments for rGBM, re-resections remain prominent in our arsenal. This study evaluates the impact of reoperation on post-progression survival (PPS) considering rGBM genetic makeup. METHODS: To assess the genetic heterogeneity and treatment-related changes (TRC) roles in re-operated or medically managed rGBMs,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Glioblastoma

Share to Neoplasm Recurrence, Local

Share to Prognosis

Share to Reoperation

Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 34997451
DOI: 10.1007/s11060-021-03917-1
PMCID: PMC9338692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impacts of genotypic variants on survival following reoperation for recurrent glioblastoma.PMID 34997451Read ↗

Do the benefits of IDH mutations in high-grade glioma persist beyond the first recurrence? A multi-institutional retrospective analysisSemantic proximity Read ↗

Genomic alterations predictive of response to radiosurgery in recurrent IDH-WT glioblastoma.Semantic proximity Read ↗

Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators.Semantic proximity Read ↗

Clinical significance of histopathological features of paired recurrent gliomas: a cohort study from a single cancer center.Semantic proximity Read ↗

Prognostic relevance of resection at first recurrence in isocitrate dehydrogenase mutant lower-grade glioma: results from a retrospective, single-center, volumetric analysis.Semantic proximity Read ↗

Precision neuro-oncology: a pilot analysis of personalized treatment in recurrent glioma.Semantic proximity Read ↗

Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent GliomaSemantic proximity Read ↗

Predictive value of EGFR amplification and EGFRvIII mutation in EGFR-targeted therapy for recurrent glioblastoma: a systematic review.Semantic proximity Read ↗

Intratumoral Heterogeneity and Longitudinal Changes in Gene Expression Predict Differential Drug Sensitivity in Newly Diagnosed and Recurrent GlioblastomaSemantic proximity Read ↗

Risk Factors and Genomic Characteristics of Recurrent Meningiomas Identified Through Routine Clinical TestingSemantic proximity Read ↗

Predicting short-term recurrence and identifying key risk factors in elderly glioma patients: Insights from a retrospective cohort study.Semantic proximity Read ↗

Targeted Genomic Sequencing Reveals Different Evolutionary Patterns Between Locally and Distally Recurrent Glioblastomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.