Prognostic relevance of resection at first recurrence in isocitrate dehydrogenase mutant lower-grade glioma: results from a retrospective, single-center, volumetric analysis.

Abstract excerpt

PURPOSE: The prognostic role of repeat resection in IDH-mutant lower-grade glioma remains insufficiently defined. This observational single-center study investigated whether resection at 1st recurrence was associated with (progression-free) survival after recurrence (PFS-2; SAR) and evaluated functional outcomes. METHODS: We retrospectively analyzed 148 molecularly characterized IDH-mutant astrocytoma and...

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• Brain Neoplasms
• Follow-Up Studies
• Glioma
• Isocitrate Dehydrogenase
• Neoplasm Grading