Article
Association between paraoxonase gene and stroke in the Han Chinese population.
BMC medical genetics - 28 Jan 2013
Zhang Guojun, Li Wenjin, Li Zhiqiang, Lv Hong, Ren Yonghong, Ma Ruimin, Li Xiaohong, Kang Xixiong, Shi Yongyong, Sun Yimin
Abstract excerpt
BACKGROUND: The human paraoxonase (PON) gene family has three isoforms: PON1, PON2 and PON3. These genes are implicated as potential risk factors of cerebrovascular disease and can prevent oxidative modification of low-density lipoproteins and atherosclerosis. This study evaluated the association between the genetic variants of all three PON genes and the risks of total stroke, ischemic stroke and hemorrhagic...
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