Article
Interaction among CYP2C8, EPHX2, and CYP4A11 Gene Variants Significantly Increases the Risk for Ischemic Stroke in Chinese Populations.
Journal of atherosclerosis and thrombosis - 1 Jan 2015
Yi Xingyang, Liao Duanxiu, Fu Xiuquan, Zhang Biao, Wang Chun
Abstract excerpt
AIM: Ischemic stroke (IS) is a multifactorial disease caused by environmental risk factors and genetic susceptibility. However, few studies have assessed whether gene-gene interactions among cytochrome P450 (CYP) pathway genes influence the risk of IS. The aim of the present study was to investigate the association of 10 variants of eight CYP pathway genes with IS and to determine whether these gene-gene...
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