Article
Genetic polymorphisms of ALOX5AP and CYP3A5 increase susceptibility to ischemic stroke and are associated with atherothrombotic events in stroke patients.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Mar 2015
Yi Xingyang, Zhang Biao, Wang Chun, Liao Duanxiu, Lin Jing, Chi Lifen
Abstract excerpt
BACKGROUND: The contributions of gene-gene interactions to pathogenesis of stroke remain largely elusive. The present study was designed to investigate the associations between genetic variations and ischemic stroke risk, the roles of gene-gene interactions in ischemic stroke, and their associations with atherothrombotic events. METHODS: Among 396 patients with ischemic stroke and 378 controls, we examined 8...
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