The mutation effect reaction norm (mu-rn) highlights environmentally dependent mutation effects and epistatic interactions.

Abstract excerpt

Since the modern synthesis, the fitness effects of mutations and epistasis have been central yet provocative concepts in evolutionary and population genetics. Studies of how the interactions between parcels of genetic information can change as a function of environmental context have added a layer of complexity to these discussions. Here, I introduce the "mutation effect reaction norm" (Mu-RN), a new instrument...

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