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Differential Implications of CSF3R Mutations in t(8;21) and CEBPA Double Mutated Acute Myeloid Leukemia.

Clinical lymphoma, myeloma & leukemia - 1 Jun 2022

Wang Biao, Wen Lijun, Wang Zheng, Chen Suning, Qiu Huiying

Abstract excerpt

BACKGROUND: Few data are available exploring mutations of the colony-stimulating factor 3 receptor (CSF3R) in acute myeloid leukemia (AML) in an all-round and systematic manner. The purpose of this study was to analyze the CSF3R mutations (CSF3Rmut) in AML with recurrent genetic abnormalities for potential synergistic pathomechanism. PATIENTS AND METHODS: We retrospectively screened 1102 adult de novo AML...

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PMID: 34975010
DOI: 10.1016/j.clml.2021.11.013

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