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The clinical characteristics and prognosis of Chinese acute myeloid leukemia patients with CSF3R mutations.

International journal of laboratory hematology - 1 Apr 2022

Chen Xiuhua, Xu Jing, Fang Fang, Xu Zhifang, Tan Yanhong, Chang JianMei, Muyey Daniel Muteb, Wang Hongwei

Abstract excerpt

INTRODUCTION: The colony-stimulating factor 3 receptor (CSF3R) controls the proliferation of myeloid progenitors and differentiation into neutrophils. However, the clinical features and prognostic significance of CSF3R mutations in primary acute myeloid leukemia (AML) patients are still unclear. METHODS: 158 newly diagnosed AML patients were retrospectively evaluated in our study. Amplicon-based next-generation...

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PMID: 34818692
DOI: 10.1111/ijlh.13762

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