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Article

Pan-neuronal expression of human mutant huntingtin protein in Drosophila impairs immune response of hemocytes.

Journal of neuroimmunology - 15 Feb 2022

Dhankhar Jyoti, Agrawal Namita, Shrivastava Anju

Abstract excerpt

Huntington's disease (HD) is a late-onset; progressive, dominantly inherited neurological disorder marked by an abnormal expansion of polyglutamine (poly Q) repeats in Huntingtin (HTT) protein. The pathological effects of mutant Huntingtin (mHTT) are not restricted to the nervous system but systemic abnormalities including immune dysregulation have been evidenced in clinical and experimental settings of HD....

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Identifiers

PMID: 34973473
DOI: 10.1016/j.jneuroim.2021.577801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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